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Pyridoxine, the form of vitamin B6 found in seeds, nuts, fruit, and green vegetables, is an extremely inexpensive and extremely useful supplement.
As you will find elsewhere on this site, pyrixodine supplementation can support recovery from acne and rosacea, many forms of autism, both attention deficit disorder and attention deficit-hyperactivity disorder (ADHD), rheumatoid although not osteoarthritis, most allergies, depression (and help make 5-HTP for depression work better), high homocysteine, heart disease, high cholesterol, immune deficiency, morning sickness, depression associated with pregnancy, depression associated with oral contraceptive use, premenstrual syndrome, menopause symptoms, age-related cognitive decline, seborrhea, dandruff, chapped lips, conjunctivitis, bladder infections, high blood pressure, water retention, diabetic kidney disease, asthma, carpal tunnel syndrome, canker sores, some forms of schizophrenia, vertigo,and overweight. But are there problems if you get too much?
It's really difficult to take too much pyridoxine. The recommended daily intakes at various stages of life are:
It's not possible to overdose on B6 from food. To get a potentially toxic dose of B6 causing pyridoxine side effects from fruit, for example, one would need to eat 2,500 bananas a day.
Most multivitamins contain just 2.0 milligrams of the pyridoxine form of B6. Neurological symptoms such as burning, stinging, and numbness occur when taking 1,000 milligrams a day. The United States Food and Drug Administration establishes a 10-fold safety margin, setting the upper limit at 100 milligrams per day. Australia and New Zealand set the limit at 50 milligrams per day, and the UK, 20 milligrams per day.
Proportionally less pyridoxine is recommended for teens, children, and infants. But at 20 milligrams per day, there have never been any reports of pyridoxine side effects.
It's more common to need more, especially if you have any of the conditions mentioned above. If you are not taking the whole bottle of multivitamins and looking for more, you won't ever overdose on pyridoxine.